There are a number of promising new molecular targets for lung cancer chemotherapy which were discussed at the Turin congress by Egbert Smit. He talked with Peter Goodwin about insulin-like growth factor inhibitors, heat shock protein and an inhibitor of angiogenesis involving the c-MET protein.
Source: American College of Cardiology Annual Meeting Chicago March 29-April1, 2008
Tony Gershlick
Tony Gershlick, University of Leicester Adnan Kastrati, Deutsches Herzzentrum, Munich
Using bivalirudin instead of heparin during angioplasty wasn’t any better for preventing death, MI or urgent revascularisation in the 4,500-patient ISAR-REACT 3 study presented at the ACC annual meeting. Tony Gershlick and Adnan Kastrati discuss the study with Peter Goodwin and Sara Freeman.
Source: American College of Cardiology Annual Meeting Chicago March 29-April1, 2008
Tony Gershlick
Tony Gershlick, University of Leicester Adnan Kastrati, Deutsches Herzzentrum, Munich
Using bivalirudin instead of heparin during angioplasty wasn’t any better for preventing death, MI or urgent revascularisation in the 4,500-patient ISAR-REACT 3 study presented at the ACC annual meeting. Tony Gershlick and Adnan Kastrati discuss the study with Peter Goodwin and Sara Freeman.
Source: European Breast Cancer Conference, Berlin, April 15-19 2008
Scientific Editors: George Canellos (Boston), Pat Price (Manchester), Gianni Bonadonna (Milan), Gordon McVie (Milan) Commenting Expert: Emiel Rutgers, Netherlands Cancer Institute, Amsterdam
Angel Rodriguez
In this edition:
1. Lapatinib: Targets Breast Cancer Stem Cells?
Angel Rodriguez, Baylor College, Houston
2. No Help Adding Neoadjuvant Capecitabine
Gunter von Minckwitz, German Breast Group, Neu-Isenberg
3. MRI Aids Breast Surgery Planning
David Martinez-Cecilia, University Hospital Reina Sofia, Córdoba
4. Aromatase Inhibitors: No Extra Heart Risk
Alain Monnier, Centre Hospitalier de Belfort, Montbéliard
5. NAB Paclitaxel For Metastatic Breast Cancer?
William Gradishar, Northwestern University, Chicago
Peter Goodwin and Sara Freeman interview conference speakers in Berlin regarding lapatinib’s apparent effect on breast cancer “stem cells”; the lack of additional benefit from adding capecitabine to standard neoadjuvant chemotherapy; evidence that MRI improves surgical planning for breast cancer; news that aromatase inhibitors do not add to cardiovascular risk when used in adjuvant therapy instead of tamoxifen; and (from a satellite symposium) an assessment of the role of nanoparticle albumin-bound paclitaxel in therapy for metastatic breast cancer.
Source: 9th European Congress: Perspectives in Lung Cancer, Torino, Italy, March 14-15, 2008
Giorgio Scagliotti Robert Pirker
GIORGIO SCAGLIOTTI, University of Turin ROBERT PIRKER, Medical University of Vienna
A heated debate took place at the European Congress on Lung Cancer in Turin between Robert Pirker who is in favor of offering adjuvant chemotherapy to selected patients who have stage I non-small cell lung cancer, and Giorgio Scagliotti who took the opposite point of view. Peter Goodwin got them together and asked them to talk about the key issues influencing their views.
Source: London School of Hygiene and Tropical Medicine
Brian Greenwood
Brian Greenwood, London School of Hygiene and Tropical Medicine Brian Greenwood has won the Hideyo Noguchi Africa Prize for his numerous achievements in tropical disease research. He talked with Derek Thorne about his work, including the pivotal research proving that bed nets can help prevent malaria.