By admin | Published:
May 30, 2006
Thomas Geisbert, US Army Medical Research, Institute of Infectious Diseases, Fort Detrick
REFERENCE: Lancet 2006;367:1399 April 29th, 2006-05-26
A vaccine developed against the Marburg virus has now been reported in the Lancet to have kept monkeys alive when used after they’ve been exposed to the infection. Thomas Geisbert and his colleagues at the US Army Medical Research Institute in Detrick, Maryland, have modified vesicular stomatitis virus for use as a Marburg vaccine. It has already worked in prophylaxis, and now the vaccine has also been found to be effective as a treatment for existing infection. Dr Geisbert talked with Peter Goodwin about his findings.
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By admin | Published:
May 29, 2006

Annual Meeting of the American College of Cardiology March 11-14, 2006, Atlanta: Single Agent Bivalirudin Better for Acute Coronary Syndromes; Ultrafiltration vs. Diuretics in Heart Failure; Salt Substitute Lowers Blood Pressure Among High Risk Individuals in China
Michael Petch, Papworth Hospital, Cambridge, UK
REFERENCE: American College of Cardiology Annual Scientific Session March 11-14, 2006, Atlanta
Michael Petch joins Derek Thorne to talk about some more of the news from the 2006 meeting of the ACC in Atlanta. Including:
- Do the results from the ACUITY study support the use of bivalirudin in all types of acute coronary syndrome? We hear from Gregg Stone, from Columbia University, New York, and Michael Lincoff, from the Cleveland Clinic, Ohio
- Ultrafiltration could be an alternative to diuretics in patients with acute decompensated heart failure, according to Maria Rosa Costanzo from the Edward Hospital for Heart Failure in Naperville
- Bruce Neal, of Sydney University, explains how a salt substitute lowered blood pressure in a group of high risk individuals in China
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By admin | Published:
May 21, 2006

Annual Meeting of the American College of Cardiology March 11-14, 2006, Atlanta: Atheroma Reversal, Statins for Acute Coronary Syndromes, Targeting Dual Antiplatelet Therapy, Clopidogrel and Drug Eluting Stents, Catheter Ablation for Atrial Fibrillation
James Tcheng, Duke University, Durham, NC
REFERENCE: American College of Cardiology Annual Scientific Session March 11-14, 2006, Atlanta
The 2006 meeting of the ACC in Atlanta heard from Steven Nissen of the Cleveland Clinic, Ohio how atheroma was observed to significantly regress among patients treated with a statin in the ASTEROID study, and from Anthony Bavry – also of the Clinic – on how early aggressive use of statins helped patients with acute coronary syndromes. Peter Goodwin discussed these findings with James Tcheng who also talks about the CHARISMA trial of dual anti-platelet therapy reported to the ACC by the Cleveland Clinic’s Deepak Bhatt, the BASKET study of late stent thrombosis in drug eluting stents presented in Atlanta by Matthias Pfisterer from the University of Basel, and results of Carlo Pappone from San Raffaele University, Milan, on radio frequency ablation for paroxysmal atrial fibrillation.
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By admin | Published:
May 21, 2006
Paul Haggarty, Aberdeen University
REFERENCE: Lancet 2006;367:1513
Folic acid may increase the chance of a twin birth for women undergoing in-vitro fertilisation, according to a recent study published in the Lancet. This finding could present IVF practitioners with something of a dilemma, because on the one hand, twin births are associated with a higher risk of complications for mother and babies; but on the other, folate is an important supplement for women trying to conceive, because it reduces the incidence of neural tube defects such as spina bifida. Paul Haggarty from Aberdeen University told Derek Thorne more about the investigation.
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By admin | Published:
May 9, 2006
Sebastian L. Johnston, Imperial College, London
REFERENCE: N Engl J Med 2006;354:1589
Despite the guidelines recommendation that antibiotics should not normally be used when treating asthma exacerbations, a study published in the New England Journal of Medicine has now shown a benefit. A controlled study with 278 adult patients showed a reduction of asthma symptoms when the ketolide telithromycin was used as compared with placebo. Investigator Sebastian Johnston told Peter Goodwin that more research needs to be done before changing practice.
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Posted in Medicine | Tagged antibiotic, asthma |