
Jeremiah Ngondi, Cambridge University
Audio Journal of Oncology - September 1st, 2006
![]() Mark Socinski |
![]() Bruce Johnson |
![]() Neil Shah |
![]() Doug Smith |
REFERENCE: Abstract 7001
Mark A. Socinski, Univerisity of North Carolina, Chapel Hill
The use of anti-angiogenic therapy for treating patients with non-small cell lung cancer received a boost at the 2006 ASCO Annual Meeting in Atlanta by results from a study looking at the use of sunitinib, a multi-targeted oral drug that achieved partial responses and stable disease among pretreated patients with non-small cell lung cancer. Mark Socinski from the University of North Carolina at Chapel Hill said the results suggest that sunitinib may be even more useful when used in earlier stages of treatment.
REFERENCE: Abstract 6507
Neil Shah, University of California, San Francisco
One of the options for treating patients with chronic phase chronic myeloid leukemia resistant to imatinib might be the new targeted therapy dasatinib. ASCO delegates heard more from Neil Shah, of the University of California in San Francisco.
REFERENCE: Abstract 6509
Doug Smith, Johns Hopkins Cancer Center, Baltimore
A vaccine for chronic myeloid leukemia has produced molecular remissions in a small number of patients. Results were presented at the 2006 ASCO meeting by Doug Smith of Johns Hopkins Cancer Center in Baltimore, who described to Derek Thorne how the vaccine has been performing, and why chronic myeloid leukemia might be a good disease in which to use this approach.

Miia Kivipelto, Karolinska Institute, Stockholm
Audio Journal of Oncology - August 15th 2006
![]() Joan Houghton |
![]() Elizabeth Barrett-Connor |
![]() Fran Balkwill |
![]() Carl Christophe Schimanski |
REFERENCE: American Association for Cancer Research 97th Annual Meeting April 1-5, 2006, Washington DC. Education Session
Fran Balkwill, Barts Hospital, London
Chemo-attractant molecules called chemokines that direct the migration of immune cells around the body could become important new weapons in the cancer doctor’s therapeutic armory, according to Fran Balkwill who chaired an education session at the American Association for Cancer Research Annual Meeting. In difficult-to-treat diseases like ovarian cancer, chemokine modulation offers the possibility of contributing alternative targeted components to anticancer regimens.
REFERENCE: American Association for Cancer Research 97th Annual Meeting April 1-5, 2006, Washington DC. Abstract 406
Carl Christophe Schimanski, University of Mainz
The chemokine in the human body known as CXCR4 might be an omnipresent inductor of the metastatic process, according to Carl Schimanski who presented data on CXCR4 expression in hepatocellular carcinoma biopsies and related it to metastatic tumor properties in patients. He told the AACR conference that the recent availability of chemokine antagonists holds out the promise of modulating metastasis and extending patient survival.
