Archive for April, 2007
Audio Journal of Global Health Issues: Drug Eluting Stents, PFO Closure: Indications Not Obvious">Audio Journal of Global Health Issues: Drug Eluting Stents, PFO Closure: Indications Not Obvious
MARK REISMAN, Swedish Medical Center, Seattle
REFERENCE: ABSTRACT ACP Internal Medicine 2007, ERA 002
Drug eluting stents may not always be the automatic choice over the bare metal variety for patients requiring intervention, despite the important clinical advantages that have been emerging from their introduction recently. This is according to Mark Reisman who gave the Internal Medicine 2007 conference in San Diego his latest insights from the rapidly changing world of interventional cardiology. At this (recently renamed) annual meeting of the American College of Physicians he also discussed the difficult question of which patients are candidates for PFO closure, and what the clinical objectives of this might be: including the possible reduction of migraine headaches. After his session he talked with Peter Goodwin.
Drug eluting stents may not always be the automatic choice over the bare metal variety for patients requiring intervention, despite the important clinical advantages that have been emerging from their introduction recently. This is according to Mark Reisman who gave the Internal Medicine 2007 conference in San Diego his latest insights from the rapidly changing world of interventional cardiology. At this (recently renamed) annual meeting of the American College of Physicians he also discussed the difficult question of which patients are candidates for PFO closure, and what the clinical objectives of this might be: including the possible reduction of migraine headaches. After his session he talked with Peter Goodwin.
Audio Journal of Global Health Issues: Patient Power Best to Manage Diabetes">Audio Journal of Global Health Issues: Patient Power Best to Manage Diabetes
HILARY SELIGMAN, University of California, San Francisco
REFERENCE: ABSTRACT Press Release, San Diego ACP 2007
Doctors can best help their patients with diabetes by taking particular care to put management into the hands of the patients themselves, rather than asking them to slavishly follow the doctors’ instructions, conference-goers in San Diego heard. A new ACP guide booklet for diabetes management called “Living with Diabetes”, designed to be used by patients in consultation with their doctors, has made concrete improvements in diabetic management, according to results from a study released during the American College of Physicians annual meeting. Peter Goodwin talked with one of the authors of the new initiative, Hilary Seligman.
Doctors can best help their patients with diabetes by taking particular care to put management into the hands of the patients themselves, rather than asking them to slavishly follow the doctors’ instructions, conference-goers in San Diego heard. A new ACP guide booklet for diabetes management called “Living with Diabetes”, designed to be used by patients in consultation with their doctors, has made concrete improvements in diabetic management, according to results from a study released during the American College of Physicians annual meeting. Peter Goodwin talked with one of the authors of the new initiative, Hilary Seligman.
Study on Longevity Genes And Aging Raises Prospects for Therapy
NIR BARZILAI, Albert Einstein College of Medicine, New York
REFERENCE: ABSTRACT ERA 001 ACP 2007, San Diego
The prospect of modulating the activity of “longevity genes” to extend life was held out at a special session of the ACP Internal Medicine annual meeting in San Diego. Nir Barzilai, Director of the Institute for Aging Research in New York, presented data from his group’s study of patients up to 100 years old and over which have shown that specific genes are related to longevity and freedom from physical illness. Afterwards he talked about his findings and the clinical opportunities they present with Peter Goodwin.
The prospect of modulating the activity of “longevity genes” to extend life was held out at a special session of the ACP Internal Medicine annual meeting in San Diego. Nir Barzilai, Director of the Institute for Aging Research in New York, presented data from his group’s study of patients up to 100 years old and over which have shown that specific genes are related to longevity and freedom from physical illness. Afterwards he talked about his findings and the clinical opportunities they present with Peter Goodwin.
Rural to Urban Migration: Cardiovascular Health Risks Assessed in Lima, Peru
JAIME MIRANDA, London School of Hygiene and Tropical Medicine, Peru
The consequences of migration from rural to urban areas in Peru has provided an opportunity for studying the impact of a radically altered lifestyle and diet upon health. Jaime Miranda is investigating the disease patterns among migrants from the Andes Mountains and the Amazon Jungle regions of Peru in the capital, Lima. He discussed his group’s investigation with Peter Goodwin.
Once-And-For-All TB Assay Brings Cheap, Sensitive, Specific, Seven-Day Diagnosis and Drug-Susceptibility Testing
DAVID MOORE, Imperial College, London and Lima
REFERENCE: N Engl J Med 355: 1539-50
A new test for TB, trialled in Peru, has proved more powerful and yet faster and cheaper than alternatives, making it especially suitable for use in resource-limited settings where tuberculosis is becoming more rampant, partly through the world-wide advance of HIV. David Moore and his colleagues have published results in the New England Journal of Medicine of a massive investigation conducted in Lima with nearly 4 000 samples of the sputum test called: Microscopic-Observation Drug-Susceptibility (MODS) Assay. Their findings promise not only to improve diagnosis and save lives in developing countries and other settings with limited health-care resources, but also out-perform costly gold-standard technology-intensive TB diagnosis methods currently used where cash is not a problem. The MODS test, David Moore told Peter Goodwin during a visit to Peru, gives sensitive and specific diagnosis in as little as seven days, and concurrently yields drug susceptibility data which helps combat multi-drug resistant TB.
A new test for TB, trialled in Peru, has proved more powerful and yet faster and cheaper than alternatives, making it especially suitable for use in resource-limited settings where tuberculosis is becoming more rampant, partly through the world-wide advance of HIV. David Moore and his colleagues have published results in the New England Journal of Medicine of a massive investigation conducted in Lima with nearly 4 000 samples of the sputum test called: Microscopic-Observation Drug-Susceptibility (MODS) Assay. Their findings promise not only to improve diagnosis and save lives in developing countries and other settings with limited health-care resources, but also out-perform costly gold-standard technology-intensive TB diagnosis methods currently used where cash is not a problem. The MODS test, David Moore told Peter Goodwin during a visit to Peru, gives sensitive and specific diagnosis in as little as seven days, and concurrently yields drug susceptibility data which helps combat multi-drug resistant TB.
Audio Journal of Oncology in Advance - April 15th, 2007 - Bisphosphonates Recommended for Lung Cancer Bone Metastases
PETER HARPER, Guy’s Hospital, London
REFERENCE: “Management of Tumour and Treatment Related Symptoms” section, Perspectives in Lung Cancer, Seville
Bisphosphonates may be more suited for improving the outlook among patients with lung cancer who have bone metastases compared to palliative radiation and analgesics, according to Peter Harper, who assessed the data from recent studies for delegates at the Lung Cancer conference in Seville. He talked with Peter Goodwin.
Bisphosphonates may be more suited for improving the outlook among patients with lung cancer who have bone metastases compared to palliative radiation and analgesics, according to Peter Harper, who assessed the data from recent studies for delegates at the Lung Cancer conference in Seville. He talked with Peter Goodwin.
To listen this episode please go to ASCO Audio Journal of Oncology in Advance Presentations.
Audio Journal of Cardiovascular Medicine: “COURAGE” Trial Assessed: New Guidelines for Patients with Stable Coronary Disease?">Audio Journal of Cardiovascular Medicine: “COURAGE” Trial Assessed: New Guidelines for Patients with Stable Coronary Disease?
HARVEY WHITE, Auckland City Hospital
REFERENCE: ACC 2007 & N Engl J Med 356: March 2007
The finding from the COURAGE trial: that angioplasty adds no benefits to optimal medical therapy alone for patients with stable coronary disease, should give pause for thought among clinicians all over the world, according to Harvey White, who discussed the new data with Peter Goodwin.
The finding from the COURAGE trial: that angioplasty adds no benefits to optimal medical therapy alone for patients with stable coronary disease, should give pause for thought among clinicians all over the world, according to Harvey White, who discussed the new data with Peter Goodwin.
Audio Journal of Oncology in Advance - April 1st, 2007 - reporting From: Journal of Clinical Oncology, January 20th, 2007 & December 20, 2006
George Canellos
Robert Motzer
Hormone Replacement Therapy: Better Survival With Colorectal Cancer
REFERENCE: J Clin Oncol 24:5680-5686
GEORGE CANELLOS, Dana-Farber Cancer Institute, Boston
Using postmenopausal estrogen replacement before the diagnosis of colorectal cancer was associated with better cancer-specific and overall mortality. This is the finding of a study by Jennifer Chan and colleagues from the Dana-Farber Cancer Institute and Massachusetts General Hospital in Boston. Peter Goodwin talked with George Canellos about the finding and its implications for therapy.
High-Dose Chemotherapy With Stem Cell Rescue: No Benefit as First-Line Therapy in Metastatic Germ Cell Tumors
REFERENCE: J Clin Oncol 25: 247-256
GEORGE CANELLOS, Dana-Farber Cancer Institute, Boston
No advantage has emerged from high-dose chemotherapy as first-line therapy in patients with poor- and intermediate-risk metastatic germ cell tumors. A phase III randomized study comparing high-dose with standard-dose chemotherapy has been published in the Journal of Clinical Oncology by a group led by Robert Motzer of Memorial Sloan-Kettering Cancer Center in New York. George Canellos discusses these findings with Peter Goodwin and puts them into context with other recent related study findings.
To listen this episode please go to ASCO Audio Journal of Oncology in Advance Presentations.
Obesity, Car Travel, Climate Change: Linked?»
Phil Edwards, London School of Hyugiene and Tropical Medicine
LSHTM Audio News
Obesity Linked to Motor Transport And Climate Change
Peter Goodwin questions Phil Edwards of the London School of Hygiene and Tropical Medicine about "competition between stomachs and petrol tanks" discussed in a letter he and his colleague Ian Roberts have written to the medical magazine: The Lancet.Phil Edwards, London School of Hyugiene and Tropical Medicine
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