ACC 2006

This category contains 17 posts

Pexelizumab Reduces Mortality in High Risk Coronary Artery By-Pass Patients

Peter Smith
Peter Smith, Duke University Medical Center, Durham, NC
Late Breaking Clinical Trials, ACC Atlanta 2006, Sunday 12th March 2006
The drug pexelizumab, targeting inflammation, reduced the risk of death among patients about to have coronary artery by-pass grafting in the PRIMOCABG-II study. Peter Smith of Duke University told the ACC about his group’s findings.

Salt Substitute Substantially Lowers Blood Pressure Among High-Risk Individuals

Bruce Neal
Bruce Neal, The George Institute, University of Sydney
Late Breaking Clinical Trials, ACC Atlanta 2006, Sunday 12th March 2006
Because high levels of salt consumption in rural areas of northern China are a common cause of cardiovascular morbidity, Bruce Neal and his group introduced potassium and magnesium into local diets in the China Salt Substitute Study or CSSS. This has made a beneficial impact on blood pressure.

CHARISMA Trial: Add Clopidogrel to Aspirin? Not for Lower Risk Patients

Deepak Bhatt
Deepak Bhatt, Cleveland Clinic, Ohio
American College of Cardiology Annual Scientific Session March 11-14, 2006, Atlanta
The idea of adding clopidogrel anti-platelet therapy to standard aspirin therapy among patients with multiple risk factors for coronary disease is not supported by the CHARISMA study findings reported at the ACC conference in Atlanta. But Audio Medica heard from Deepak Bhatt of the Cleveland Clinic that the study found patients with established cardiovascular disease can benefit.

Single Agent Bivalirudin Better for Acute Coronary Syndromes

Gregg Stone
Gregg Stone, Columbia University Medical Center, New York
American College of Cardiology Annual Scientific Session March 11-14, 2006, Atlanta
A superiority for the anti-clotting drug bivalirudin for treating patients with acute coronary syndromes was detected when this was used as monotherapy, but not when this direct thrombin inhibitor was combined with glycoprotein IIb/IIIa inhibition. Thus found the ACUITY trial reported to the ACC’s Atlanta meeting by Gregg Stone of Columbia University. He told Audio Medica the bottom line finding from the study.

Bivalirudin in ACS: The Acuity Study Findings

Michael Lincoff
Michael Lincoff, Cleveland Clilnic, Cleveland Ohio
American College of Cardiology Annual Scientific Session March 11-14, 2006, Atlanta
The full picture of how bivalirudin is emerging as a treatment without also using glycoprotein IIb/IIIa inhibition in cases of acute coronary syndrome was painted at the Atlanta meeting by Michael Lincoff from the Cleveland Clinic.

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