Category: Cardiovascular

cardiology

Heart Attacks Drop After Smoking Ban in Ireland

September 5, 2007
edmond cronin Heart Attacks Drop After Smoking Ban in Ireland
Edmond Cronin

REFERENCE: Abstract 3506, European Society of Cardiology Congress, 2007, 1-5 September, Vienna, Austria
EDMOND CRONIN, Cork University Hospital
Study data that support banning smoking in public places were unveiled at the ESC congress by a team from Ireland. After the smoking ban in 2004, admissions for acute coronary syndromes dropped, and lead author Edmond Cronin explained the significance of his findings to Derek Thorne.

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Looking for Atherosclerosis in the Legs Could Save Lives

September 5, 2007
curt diehm Looking for Atherosclerosis in the Legs Could Save Lives
Curt Diehm

REFERENCE: European Society of Cardiology Congress, 2007, 1-5 September, Vienna, Austria
CURT DIEHM, University of Heidelberg
Peripheral arterial disease (PAD) can be diagnosed easily by a test using the ankle brachial index (ABI) and its presence can indicate a high risk of myocardial infarction. Curt Diehm explained his findings to Derek Thorne, while Peter Goodwin got expert comment from Freek Verheugt.

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Blood Pressure, Cholesterol, Smoking: Key Factors in New European Guidelines to Prevent Heart Disease

September 5, 2007
ian graham Blood Pressure, Cholesterol, Smoking: Key Factors in New European Guidelines to Prevent Heart Disease
Ian Graham

REFERENCE: 15:40 Sunday 2nd Sept CV Disease Prevention, European Society of Cardiology Congress, 2007, 1-5 September, Vienna, Austria
IAN GRAHAM, Trinity College, Dublin
Three key modifiable factors determine cardiovascular risk: blood pressure, lipid profile and smoking. That’s according to Ian Graham who summarized the latest European Society of Cardiology guidelines for preventing heart disease. Other factoirs including the metabolic syndrome, gender, body mass index and activity levels generally also involve the three master factors, and there are big benefits to be gained from modifying each of the key factors singly even when a patient can’t change one or more of them. Peter Goodwin discussed the new guidelines with Professor Ian Graham during the cardiology conference in Vienna.

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Chronic Stable Angina: Should ESC Guidelines on Clopidogrel as Pre-Treatment to Planned Coronary Angiography be Changed?

September 3, 2007
petr widimsky Chronic Stable Angina: Should ESC Guidelines on Clopidogrel as Pre Treatment to Planned Coronary Angiography be Changed?
Petr Widimsky
eckart fleck Chronic Stable Angina: Should ESC Guidelines on Clopidogrel as Pre Treatment to Planned Coronary Angiography be Changed?
Eckhart Fleck

REFERENCE: Hot Line II Monday 3rd Sept, European Society of Cardiology Congress, 2007, 1-5 September, Vienna, Austria
PETR WIDIMSKY, Charles University, Prague
COMMENT: ECKART FLECK, Deutsches Herzzentrum Berlin

The ESC guideline suggesting all patients with chronic stable angina having coronary angiography should have clopidogrel pre-treatment is now being questioned following findings of the PRAGUE-8 Study, which randomized patients to receive the anti-platelet agent either non selectively before angiography, or selectively after angiography in those considered to need PCI. The PRAGUE investigators concluded that the ESC guideline was unjustified for the treatment of elective angiography in chronic stable angina, and that the previous practice of selective administration of clopidogrel should be resumed. Nicola Solomon talked with Petr Widimsky at the ESC Congress in Vienna. Derek Thorne heard comments on the findings from Eckart Fleck.

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Cardiovascular Disease Prevention: Important to Look at Social Deprivation

September 3, 2007
hugh tunstall pedoe Cardiovascular Disease Prevention: Important to Look at Social Deprivation
Hugh Tunstall-Pedoe

REFERENCE: Abstract 1075, European Society of Cardiology Congress, 2007, 1-5 September, Vienna, Austria
HUGH TUNSTALL-PEDOE, University of Dundee
New data presented at the ESC congress suggests that social deprivation should be considered when considering a cardiac risk score – not just smoking, blood pressure, HDL and cholesterol. Derek Thorne got the details and implications from Hugh Tunstall-Pedoe of Dundee University.

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Drug Eluting Stent Shows Great Benefit in Chronic Total Occlusions

September 3, 2007
gerald werner Drug Eluting Stent Shows Great Benefit in Chronic Total Occlusions
Gerald Werner

REFERENCE: Abstract 925, European Society of Cardiology Congress, 2007, 1-5 September, Vienna, Austria
GERALD WERNER, Klinikum Darmstadt, Germany
The ESC congress in Vienna heard that drug eluting stents are highly effective in chronically occluded arteries, when compared with bare metal stents. Derek Thorne got more on this German study from Gerald Werner, of Klinikum Darmstadt in Germany.

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Enoxaparin Superior to Unfractionated Heparin for STEMI at 12 months Follow Up: ExTRACT-TIMI 25 Trial

September 3, 2007
david morrow Enoxaparin Superior to Unfractionated Heparin for STEMI at 12 months Follow Up: ExTRACT TIMI 25 Trial
David Morrow

REFERENCE: Abstract 1027, Clinical Trial Update I, European Society of Cardiology Congress, 2007, 1-5 September, Vienna, Austria
DAVID MORROW, Brigham and Women’s Hospital, Boston
Further data to support the use of enoxaparin has come out of the latest update from the ExTRACT-TIMI 25 study. It shows at 12 months follow up, that the benefits of enoxaparin are durable and still superior to unfractionated heparin for patients with ST elevation myocardial infarction undergoing fibrinolytic therapy. Sarah Maxwell interviewed David Morrow at the Vienna meeting.

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BNP Test: Key Diagnostic Step for Heart Failure (PEP Study)

September 3, 2007
john cleland BNP Test: Key Diagnostic Step for Heart Failure (PEP Study)
John Cleland
maarten simoons BNP Test: Key Diagnostic Step for Heart Failure (PEP Study)
Maarten Simoons

REFERENCE: Hot Line 1 Sunday 11:00 2 Sept, European Society of Cardiology Congress, 2007, 1-5 September, Vienna, Austria
JOHN CLELAND, University of Hull
COMMENT: MAARTEN SIMOONS, Erasmus University, Rotterdam

A new blood test using brain natriuretic peptide or BNP could become the primary step for diagnosing heart failure. This is according to the latest results from the Perindopril for Elderly People with Chronic Heart Failure or PEP-CHF study that measured levels of BNP in heart failure patients who had previously had echocardiograms. It found that many patients had been misdiagnosed. These results suggest that the BNP test should go before the echocardiogram for diagnosing patients with heart failure. Sarah Maxwell discussed the findings with study author John Cleland at the ESC meeting in Vienna.
Maarten Simoons of Erasmus University in Rotterdam commented on the PEP study findings.

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Immediate Angioplasty After Throbolysis Can Save Lives

September 3, 2007
carlo dimario Immediate Angioplasty After Throbolysis Can Save Lives
Carlo Di Mario
eckart fleck Immediate Angioplasty After Throbolysis Can Save Lives
Eckhart Fleck

REFERENCE: Hot Line II, European Society of Cardiology Congress, 2007, 1-5 September, Vienna, Austria
CARLO DI MARIO, Royal Brompton Hospital, London
COMMENT: ECKART FLECK, Deutsches Herzzentrum Berlin

The CARESS study from Milan and London has shown that for younger, high-risk patients experiencing a myocardial infarction there can be a clear benefit from performing angioplasty as soon as it is available after using lytics with anti-platelet therapy in situations where primary angioplasty is not available. This answers a huge un-met need of what is best to do for patients who are admitted initially to a centre where primary percutaneous intervention is not an immediate option. At the cardiology congress in Vienna Carlo Di Mario told Peter Goodwin that patients at lower risk of bleeding who can proceed to angioplasty should do so.
Eckhart Fleck added his comments about following lytic therapy with angioplasty.

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Audio Journal of Cardiovascular Medicine: Reduced Mortality and Repeat MI with Enoxaparin for Patients with ST Elevation Myocardial Infarction

May 14, 2007
harvey white Audio Journal of Cardiovascular Medicine: Reduced Mortality and Repeat MI with Enoxaparin for Patients with ST Elevation Myocardial Infarction

HARVEY WHITE, Auckland City Hospital, New Zealand

REFERENCE: European Heart Journal Advanced On-Line Publication April 24th, 2007
Enoxaparin could be the new standard anti-thrombotic therapy for patients receiving fibrinolysis for ST elevation myocardial infarction. This finding is from the double-blind EXTRACT-TIMI 25 Trial which compared the low molecular weight heparin with unfractionated heparin and saw a consistent treatment superiority from enoxaparin with a reduction in repeat myocardial infarction and mortality. Sarah Maxwell spoke with the principal investigator Harvey White at the Auckland City Hospital in New Zealand.

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Fewer Major Bleeding Events with Bivalirudin For Patients with Acute Coronary Syndromes: The ACUITY study

May 3, 2007
harvey white Fewer Major Bleeding Events with Bivalirudin For Patients with Acute Coronary Syndromes: The ACUITY study

HARVEY WHITE, Auckland City Hospital, New Zealand

REFERENCE: ACUITY Trial, ACC.07 Scientific Session and i2 Innovations Summit. Presentation Number: 2414-5
Patients with acute coronary syndromes who take bivalirudin have fewer major bleeding events and a lower incidence of late stent thrombosis compared with those who receive standard heparin therapy. This is the finding of one year results from the ACUITY study announced by Gregg Stone of Columbia University, New York during the American College of Cardiology annual meeting that took place in New Orleans. Sarah Maxwell asked Harvey White at the Auckland City Hospital in New Zealand to comment about the ACUITY investigation.

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Audio Journal of Cardiovascular Medicine: “COURAGE” Trial Assessed: New Guidelines for Patients with Stable Coronary Disease?

April 6, 2007
harvey white Audio Journal of Cardiovascular Medicine: COURAGE Trial Assessed: New Guidelines for Patients with Stable Coronary Disease?

HARVEY WHITE, Auckland City Hospital

REFERENCE: ACC 2007 & N Engl J Med 356: March 2007
The finding from the COURAGE trial: that angioplasty adds no benefits to optimal medical therapy alone for patients with stable coronary disease, should give pause for thought among clinicians all over the world, according to Harvey White, who discussed the new data with Peter Goodwin.

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