Category: London School of Hygiene & Tropical Medicine

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Starting Antiretroviral Therapy Can Trigger Leprosy

September 20, 2007
diana lockwood Starting Antiretroviral Therapy Can Trigger Leprosy
Diana Lockwood

REFERENCE:47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007
DIANA LOCKWOOD, London School of Hygiene and Tropical Medicine
ICAAC delegates heard that ‘hidden’ leprosy can be triggered in some patients who are receiving HIV antiretroviral therapy. So what might this mean for the countries that are rolling out this therapy to large numbers of people? Derek Thorne discussed the issue with Diana Lockwood of the London School of Hygiene and Tropical Medicine.

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LSHTM Audio News Special: Global Mental Health

September 15, 2007
vikram patel LSHTM Audio News Special: Global Mental Health
Vikram Patel

shekhar saxena LSHTM Audio News Special: Global Mental Health
Shekhar Saxena


Mental Health is a major part of the global disease burden, but more needs to be done to make sure support, treatments and policies are in place. That’s according to a series of articles, published in The Lancet, which have looked at this very topic. The audio news team went to meet some of the authors:
Graham Thornicroft, of Kings College London, who talked about the size of the problem;
Vikram Patel, of the London School of Hygiene and Tropical Medicine, who discussed measures to take and choices that need to be made;
and Shekhar Saxena, from the World Health Organisation, who has calculated the costs involved.

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LSHTM Audio News Special: Energy and Health

September 13, 2007
paul wilkinson LSHTM Audio News Special: Energy and Health
Paul Wilkinson

How does energy use lead to poor health?

REFERENCE: Lancet, September, 2007
PAUL WILKINSON, London School of Hygiene and Tropical Medicine
Paul Wilkinson, of the London School of Hygiene and Tropical Medicine, says there are many ways energy use impacts on health, and he explained the situation in the developing world.

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London School of Hygiene & Tropical Medicine Audio News Review, September 12th, 2007

September 12, 2007
jaime miranda London School of Hygiene & Tropical Medicine Audio News Review, September 12th, 2007
Jaime Miranda

Road-Side Tranexamic Acid Therapy to Reduce Mortality and Blood Transfusions after Trauma?

JAIME MIRANDA, London School of Hygiene and Tropical Medicine, Peru
The multi-national CRASH trial investigates whether the antifibrinolytic agent, tranexamic acid normally used to reduce bleeding during surgery can also be used as a first-aid to cut mortality and the need of blood transfusion immediately after trauma. Jaime Miranda, based in Lima, Peru, described to Peter Goodwin how the trial could benefit the developing world in particular.

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London School of Hygiene & Tropical Medicine Audio News Review, August 31st, 2007

August 31, 2007
philippe mayaud London School of Hygiene & Tropical Medicine Audio News Review, August 31st, 2007
Philippe Mayaud

Herpes Simplex Therapy Reduces HIV Activity in Co-Infected Patients

REFERENCE: N Engl J Med 2007; 356: 790-9
PHILIPPE MAYAUD, London School of Hygiene and Tropical Medicine
It is possible to reduce HIV activity in patients who are co-infected with HIV and herpes simplex type 2. Philippe Mayaud tells us about the study which showed reduced HIV concentration in the blood and vagina when co-infected patients underwent continuous treatment with anti-herpes agent valacyclovir.

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London School of Hygiene & Tropical Medicine Audio News Review, August 28th, 2007

August 30, 2007
pat doyle London School of Hygiene & Tropical Medicine Audio News Review, August 28th, 2007
Pat Doyle

Increased Miscarriage Risk in Women with Low Body Mass Index

REFERENCE: BJOG 2007 114:170
PAT DOYLE, London School of Hygiene and Tropical Medicine
Underweight women with a BMI below 18.5 have a 70 per cent increase in their risk of miscarriage according to a study published in the British Journal of Obstetrics and Gynaecology. Pat Doyle gave us the details.

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London School of Hygiene & Tropical Medicine Audio News Review, August 25th, 2007

August 25, 2007
david moore London School of Hygiene & Tropical Medicine Audio News Review, August 25th, 2007
David Moore

Seven-Day Low-Cost Tuberculosis Diagnosis

REFERENCE: N Engl J Med 355: 1539-50
DAVID MOORE, Imperial College, London and Lima
A new test for TB (reported in the New England Journal of Medicine) has proved more powerful, faster and yet cheaper than any alternative. David Moore explains how the Microscopic-Observation Drug-Susceptibility (MODS) Assay is highly sensitive and specific, and also yields drug susceptibility data.

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London School of Hygiene & Tropical Medicine Audio News

August 16, 2007
simon lewin London School of Hygiene & Tropical Medicine Audio News
Simon Lewin

Adherence to TB Medication

PLoS Med 4(7):e238. doi:10.1371/journal.pmed.0040238
SIMON LEWIN, London School of Hygiene and Tropical Medicine
A new systematic review has shown that we don’t understand well enough the reasons for poor adherence to tuberculosis medication. Simon Lewin of the London School of Hygiene and Tropical Medicine calls for a better approach in the area.

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Tuberculosis: Non-Adherence to Treatment is a Major Obstacle to Therapy Success

August 9, 2007
simon lewin Tuberculosis: Non Adherence to Treatment is a Major Obstacle to Therapy Success
Simon Lewin

REFERENCE: PLoS Med 4(7):e238. doi:10.1371/journal.pmed.0040238
SIMON LEWIN, London School of Hygiene and Tropical Medicine
Non-adherence is a big factor reducing the efficacy of tuberculosis treatment according to a review of research released by the Public Library of Science’s online medical journal, PLoS Medicine. The article suggests that more needs to be done to resolve barriers to therapy compliance in order to help reduce the global burden of tuberculosis. Nicola Solomon interviewed Simon Lewin.

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London School of Hygiene & Tropical Medicine Audio News – July 26th, 2007

July 26, 2007
chris curtis London School of Hygiene & Tropical Medicine Audio News   July 26th, 2007
Chris Curtis

Malaria Nets Should be Mass Distributed

CHRIS CURTIS, London School of Hygiene and Tropical Medicine
The current method of distributing insecticidal nets for malaria isn’t working well enough. Chris Curtis explains what needs to be done.

jean jannin London School of Hygiene & Tropical Medicine Audio News   July 26th, 2007
Jean Jannin

Renewed Battle Against Chagas Disease

JEAN JANNIN, World Health Organisation
MICHAEL MILES, London School of Hygiene and Tropical Medicine

Jean Jannin of the WHO discusses the organisation’s new push to eliminate Chagas Disease; and Michael Mills explains how London School research will contribute.

harold margolis London School of Hygiene & Tropical Medicine Audio News   July 26th, 2007
Harold Margolis

Quiet Progress for the Dengue Vaccine

REFERENCE: www.pdvi.org
HAROLD MARGOLIS, Pediatric Dengue Vaccine Initiative, Seoul
Harold Margolis, director of the Pediatric Dengue Vaccine Initiative, describes current progress in the development of a vaccine for dengue fever.

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Rosiglitazone for Patients with Diabetes: Cardiovascular Outcomes Trial Findings

July 15, 2007
stuart pocock Rosiglitazone for Patients with Diabetes: Cardiovascular Outcomes Trial Findings
Stuart Pocock

REFERENCE: ABSTRACT N Engl J Med 2007; 357: 28-381
STUART POCOCK, London School of Hygiene and Tropical Medicine
Reassuring findings about the safety of the anti-diabetic drug rosiglitazone have been published in the New England Journal of Medicine following an interim analysis of the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes (RECORD) study. This latest publication follows a meta-analysis in June 2007 by Nissen and Wolski which raised doubt about the safety of the drug. Nicola Solomon spoke with the RECORD trial’s statistician, Stuart Pocock, to get the latest data from this largest study specifically designed to look at cardiovascular outcomes.

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London School of Hygiene & Tropical Medicine Audio News – July 1st, 2007

July 1, 2007
mckee martin London School of Hygiene & Tropical Medicine Audio News   July 1st, 2007
Martin McKee

The Threat of Oral Tobacco

MARTIN MCKEE, London School of Hygiene and Tropical Medicine
Martin McKee on the smoking ban – and how the tobacco industry is now looking to promote oral tobacco. Is it an effort to keep people addicted?

berridge virginia London School of Hygiene & Tropical Medicine Audio News   July 1st, 2007
Virginia Berridge

Health Politics Must Involve History

REFERENCE: The Guardian, 20th June
VIRGINIA BERRIDGE, London School of Hygiene and Tropical Medicine
Virginia Berridge on how the past holds important lessons for public health in the present.

mckee martin London School of Hygiene & Tropical Medicine Audio News   July 1st, 2007
Martin McKee

Alcohol Consumption in Russian Men

REFERENCE: The Lancet 2007; 369:2001-2009
MARTIN MCKEE, London School of Hygiene and Tropical Medicine
Martin McKee also discusses the new study on alcohol and mortality in working-age Russian men, and evidence that non-beverage alcohol is a major cause of early death.

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