Vaccine for Enterotoxigenic E. coli – Travelers’ Diarrhoea

Louis Bourgeois, Johns Hopkins University, Baltimore
Among the various experiences when visiting a developing country: there’s amazement at the sounds and the colour; delight at the warmth of the people and the climate; but also, unfortunately, travelers’ diarrhea. But the main causal bacterium, enterotoxigenic E. coli – or ETEC – is also responsible for a large amount of morbidity and mortality among children who live in the developing world. So, interest was stoked at ICAAC by the possibility of an oral killed vaccine for travellers’ diarrhea which has now been used in a double blind, randomised study involving 1400 people.

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