Audio Journal of Oncology 14.1, February 2006

12.8 tb Audio Journal of Oncology 14.1, February 2006

Reporting from:
- San Antonio Breast Cancer Symposium 2005

In this edition:
The targeted drug trastuzumab may be used in place of anthracyclines for breast adjuvant chemotherapy regimens, according to the findings of Dennis Slamon, who announced the BCIRG 006 study findings to the San Antonio conference. Norman Wolmark commented.

Kathy Miller gave the Breast Cancer conference early data showing that the anti-vascular endothelial growth factor agent, bevacizumab, has improved survival among patients with metastatic breast cancer.

Dose-dense chemotherapy should be considered mainly in hormone receptor negative breast cancer patients, so said Clifford Hudis, while Martine Piccart warned against over-enthusiasm for cytotoxic chemotherapy among patients who could benefit more from endocrine treatment.

Switching from tamoxifen to anastrozole brought clear benefits according to a meta-analysis presented in San Antonio by Walter Jonat. And ductal carcinoma in situ should be treated with radiation according to Nina Bijker’s report to the conference.

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