• About
  • Licensing
  • Podcasting
  • Contact

AudioMedica.com

Medical News Interviews

  • Public Health
  • Oncology
  • Cardiovascular
  • General Medicine

Anticoagulation with warfarin can be beneficial in patients with atrial fibrillation and chronic kidney disease.

0
  • by karen
  • in News
  • — 7 Mar, 2014

STOCKHOLM, SWEDEN—A study in JAMA Anti-coagulation has reported that warfarin could be beneficial for patients with atrial fibrillation (AF) even if they have chronic kidney disease.
Patients with AF and chronic renal disease who were discharged on warfarin therapy after a myocardial infarction (MI) had lower risks of death, further MI and ischemic stroke at one year compared to those who were not taking warfarin. And the treatment did not increase bleeding. First author Juan Jesus Carrero PhD from the Karolinska Institutet in Stockholm told AudioMedica.com with MD-FM this was across the spectrum of kidney failure:
“We went from mild, moderate to severe end-stage renal disease and we observed that warfarin treatment — in each stage of chronic kidney disease — was associated with a lower rate of events,” he observed.
He explained that in the preceding two to three years practitioners had backed off from warfarin treatment in these patients after a few studies suggested it might increase the risk of bleeding, stroke and death among patients on dialysis. But that this was not now warranted.
In an editorial comment in JAMA Dr. Mintu Turakhia MD pointed out that the benefits of warfarin might not have been spotted in another setting: “Sweden does better with managing warfarin than any other country, anywhere. In the United States, we are significantly worse at managing warfarin and it’s not clear that the same benefits would be shown, ” he said in an interview.
He also said this new research had been a step forwards and that clinicians should not regard chronic kidney disease as a disqualifier for anticoagulation: “These patients are at high risk for stroke: we know that. And although the data is observational it’s a well done study and they’ve shown that you can accomplish meaningful reductions in stroke and avoid excess bleeding if you manage the warfarin carefully.”

SOURCE : Carrero J.J et al. Warfarin, Kidney Dysfunction, and Outcomes Following Acute Myocardial Infarction in Patients With Atrial Fibrillation, JAMA. 2014;311(9):919-928. doi:10.1001/jama.2014.1334.
SOURCE 2: Winkelmayer W.C. et al., Warfarin Treatment in Patients With Atrial Fibrillation and Advanced Chronic Kidney Disease: Sins of Omission or Commission?, JAMA. 2014;311(9):913-915. doi:10.1001/jama.2014.1781.
CONTRIBUTOR: Dr. Juan Jesus Carrero PhD
Assistant Professor Renal Medicine, Karolinska Institutet, Stockholm, Sweden.
CONTRIBUTOR 2: Dr. Mintu Turakhia MD
Assistant Professor of Medicine, Stanford University, California.

Share

You may also like...

  • Quitting smoking cuts risk of cataract Enzalutamide good after abiraterone 6 Feb, 2014
  • Quitting smoking cuts risk of cataract Vitamin E: safe and effective to slow progression of mild to moderate Alzheimer’s Disease 24 Jan, 2014
  • Quitting smoking cuts risk of cataract Quitting smoking cuts risk of cataract 24 Jan, 2014
  • Paracetamol Poisoning: 12-hour modified acetylcysteine treatment for paracetamol poisoning reduced side effects associated with standard regimen. Prostate cancer: Adult exposure to bisphenol-A linked to prostate cancer risk 6 Mar, 2014

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

  • Previous story Enzalutamide improves overall and progression-free survival in men with chemotherapy-naïve metastatic castration-resistant prostate cancer
  • Next story First evidence that genome editing made patients with AIDS more resistant to HIV
  • News

    • Mandeep Mehra MDCOVID-19 Co-Morbidity Risks Quantified from Three Continents SurveyMay 28, 2020
    • Ultrahypofractionated Radiation Just As Effective for Prostate CancerUltrahypofractionated Radiation Just As Effective for Prostate CancerMay 16, 2018
    • Paracetamol Poisoning: 12-hour modified acetylcysteine treatment for paracetamol poisoning reduced side effects associated with standard regimen.First evidence that genome editing made patients with AIDS more resistant to HIVMarch 8, 2014
    • Paracetamol Poisoning: 12-hour modified acetylcysteine treatment for paracetamol poisoning reduced side effects associated with standard regimen.Anticoagulation with warfarin can be beneficial in patients with atrial fibrillation and chronic kidney disease.March 7, 2014
    • Paracetamol Poisoning: 12-hour modified acetylcysteine treatment for paracetamol poisoning reduced side effects associated with standard regimen.Prostate cancer: Adult exposure to bisphenol-A linked to prostate cancer riskMarch 6, 2014
  • Related interviews

    • Ibrutinib: New Frontline Standard for Chronic…
    • Microbiome Diversity Key To Survival After…
    • New Front Line Standard for Older Patients with…
    • Genomic-led AML Clinical Decision Making Within Seven Days
    • Pembrolizumab: No Survival Gains Second Line In…
  • Home
  • News
  • Anticoagulation with warfarin can be beneficial in patients with atrial fibrillation and chronic kidney disease.

© Copyright 2021 AudioMedica.com. Typegrid Theme by WPBandit.