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Audio Journal of Cardiovascular Medicine 11.2, 2005

  • in Cardiovascular
  • — 8 Jan, 2006
Audio Journal of Cardiovascular Medicine 11.2, 2005





Reporting from:
American College of Cardiology Annual Scientific Session 2005, March 6-9, Orlando, Florida
Scientific Editors:

Michael Petch, Papworth Hospital, Cambridge
Man Fai Shiu, Walsgrave Hospital, Coventry
James Tcheng, Duke University, Durham
Harvey White, Green Lane Hospital, Auckland
Producers: Derek Thorne & Peter Goodwin
Correspondents: Derek Thorne & Peter Goodwin

In this edition:

Adnan Kastrati has found that a study comparing the two main drug eluting stents in terms of late lumen loss suggests sirolimus has the upper hand over paclitaxel among diabetic patients. Marie-Claude Morice’s study has also found sirolimus stents to be slightly superior in terms of neointimal growth rates among non-diabetic patients.

Nikolaus Marx‘s investigation shows that the oral anti-diabetic drug, pioglitazone, can be used to reduce the formation of new tissue inside a stent in non-diabetics, and could reduce restenosis rates.

John Cleland and Kenneth Ellenbogen review findings that cardiac resynchronisation – or atrial-biventricular pacing – extends life in patients with severe heart failure and cardiac dysynchrony.

Germano Di Sciascio and Lloyd Klein discuss how doubling the usual clopidogrel dose may be best in coronary intervention.

Zhenming Chen & Rory Collins found that adding clopidogrel to the usual care of patients with acute myocardial infarction is of clear benefit according to the findings of the 46,000 patient COMMIT Study. However, the use of metoprolol in the same acute MI patients is not endorsed for all patients.

Interviews in this edition:

1. Eluting Stents: Sirolimus Beats Paclitaxel in Diabetics

Adnan Kastrati, Deutsches Herzzentrum, Munich

2. Cypher or Taxus: Which Drug Eluting Stent?

Marie-Claude Morice, Institut Jacques Cartier, Paris
COMMENT: John Hirshfeld, University of Pennsylvania, Philadelphia

3. Antidiabetic Drug Prevents Restenosis in Non-Diabetics?

Nikolaus Marx, University Hospital, Ulm
COMMENT: Lloyd Klein, Rush Medical College, Chicago

4. ARTS II: Can Drug Eluting Stents Surpass CABG?

Patrick Serruys, Erasmus University, Rotterdam

5. A Rôle for Statins in Heart Failure?

Andrew Sumner, Penn State Hershey Medical Center

6. Re-Synchronisation Extends Life in Severe Heart Failure

John Cleland, University of Hull
COMMENT: Kenneth Ellenbogen, Medical College of Virginia

7. Is Cardiac Resynchronisation Therapy Cost Effective?

Arthur Feldman, Jefferson Medical College, Philadelphia

8. Amiodorone Reduces Risk of ICD Shocks

Stuart Connolly, McMaster University, Ontario
COMMENT: Jeffrey Goldberger, Northwestern University, Chicago

9. Double Dose Clopidogrel Improves PCI Outcome

Germano Di Sciascio, University Campus Biomdica Di Roma
COMMENT: Lloyd Klein, Rush Medical College, Chicago

10. Extra-Low LDL Cholesterol is Even Better!

John LaRosa, SUNY Downstate Medical Center, Brooklyn

11. Statins Before Stenting: Better Outcomes

Mandeep Singh, Mayo Clinic, Rochester

12. Calcium Antagonist plus ACE Inhibitor: Safest Blood Pressure Control

Peter Sever, Imperial College, London

13. Obesity Control: 2-Year Results with Rimonabant

Luc Van Gaal, University of Antwerp
COMMENT: Julius Gardin, St John Hospital, Detroit

14. Enoxaparin: Safe for PCI in Acute Coronary Syndromes

Harvey White, Green Lane Hospital, Auckland

15. Consistent Enoxaparin Therapy is Superior

Kenneth Mahaffey, Duke University Medical Center, Durham

16. Three-Year Results show Sirolimus Stent Still Ahead

David Holmes, Mayo Clinic, Rochester

17. Absorbable Stents: Early Results Promising?

Raimund Erbel, Universitätsklinikum, Essen

18. ENDEAVOUR: New Drug-Eluting Stent Effective?

William Wijns, Cardiovascular Center, Aalst

19. Adding Clopidogrel Benefits Patients With Acute Myocardial Infarction

Zhenming Chen & Rory Collins, Oxford University

20. CLARITY Study: Clopidogrel for STEMI

Harvey White, Green Lane Hospital, Auckland

21. Implications of COMMIT

Harvey White, Green Lane Hospital, Aukland

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