GIST Trial: Treating Glucose Levels Acutely Doesn’t Help Survival, but Does Cause Hypotension

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CHRISTOPHER GRAY, University of Newcastle
REFERENCE: Abstract No. LB2
Treating high blood sugar in the acute phases of stroke doesn’t reduce risk of death or severe disability, the GIST – UK (Glucose Insulin in Stroke Trial) has found. This is despite other trials reporting that high glucose levels are associated with increased risk of stroke. Investigators also found that treating glucose levels aggressively lowered blood pressure. To discuss this surprise result, and the background to the trial, Helen Morant talked to Chris Gray.
[audio:https://www.audiomedica.com/podcasting/cardio/020709_chris_gray.mp3]Treating high blood sugar in the acute phases of stroke doesn’t reduce risk of death or severe disability, the GIST – UK (Glucose Insulin in Stroke Trial) has found. This is despite other trials reporting that high glucose levels are associated with increased risk of stroke. Investigators also found that treating glucose levels aggressively lowered blood pressure. To discuss this surprise result, and the background to the trial, Helen Morant talked to Chris Gray.