Vaginal Progesterone Reduced Risk of Preterm Birth in Women with Short Cervix

REFERENCE: N Engl J Med 2007; 357: 426-9
KYPROS NICOLAIDES, Kings College Hospital, London
The risk of giving birth prematurely was reduced among pregnant women with short cervices by treatment with vaginally administered progesterone: whether or not they had a history of preterm delivery. Investigators from London have reported in the New England Journal of Medicine that progesterone therapy significantly reduced the risk of spontaneous delivery before 34 weeks: from a one in three chance with a placebo to one in five with progesterone. Kypros Nicolaides discussed the results with Anna Lacey.