LONDON— Intraoperative radiotherapy given at the time of lumpectomy was found to be ‘non-inferior’ to the use of conventional post-operative whole breast external beam radiotherapy and had equivalent breast cancer specific mortality but fewer non-cancer deaths. This is according to findings from the TARGIT-A study by researchers in the United Kingdom, Germany and Australia with five-year follow up data published in the Lancet. The authors give reassurance that with a ‘risk adapted’ strategy — in which patients receiving intra-operative therapy were given supplementary external beam radiation if the operation revealed they were at high risk — is a safe and effective alternative to the conventional approach and could not only benefit patients but also reduce costs. Investigators Professor Jayant S Vaidya PhD and Professor Michael Baum MB ChB FRCS describe their findings and discuss the clinical implications.
You may also like...
HAND2 gene: key to endometrial, ovarian cancer detection and treatment individualisation 15 Jan, 2014 Trifluridine with Tipiracil Lifts Survival in Refractory Gastric Cancer 11 Oct, 2018 Targeting Bone Microenvironment in Breast Cancer 27 Mar, 2015 Blood test for free tumour DNA could guide breast cancer therapy 3 Apr, 2013
- Previous story Colorectal cancer screening: survey of 11 European countries finds big mortality benefit
- Next story Disease-free survival doubles for patients treated with immunoconjugate TDM-1 for their HER-2 positive metastatic breast cancers
- Ultrahypofractionated Radiation Just As Effective for Prostate CancerMay 16, 2018
- First evidence that genome editing made patients with AIDS more resistant to HIVMarch 8, 2014
- Anticoagulation with warfarin can be beneficial in patients with atrial fibrillation and chronic kidney disease.March 7, 2014
- Prostate cancer: Adult exposure to bisphenol-A linked to prostate cancer riskMarch 6, 2014
- MMR vaccine’s non-specific effects: adherence to recommended vaccination schedules protects children against non-vaccination-specific infections tooFebruary 28, 2014