All Episodes

Patients with extensive stage small cell lung cancer did not live longer with thoracic radiotherapy added to their chemo-immunotherapy in a study reported to the American Society of Clinical Oncology 2026 Annual Meeting held in Chicago, USA. First author Bjørn Henning Grønberg MD PhD, Professor and Consultant in Oncology at the Norwegian University of Science and Technology, St. Olavs Hospital in Trondheim, Norway talked with the Audio Journal of Oncology about his group’s findings.

CHICAGO, USA—Combining the antibody-drug conjugate sacituzumab govitecan with pembrolizumab immunotherapy for patients with metastatic triple-negative breast cancers testing positive for the programmed death-ligand 1 (PD-L1) led to significant delays of disease progression after subsequent therapy in comparison with standard of care using a combination of chemotherapy with pembrolizumab. That’s according to first author of research reported at the 2026 American Association of Clinical Oncology Annual Meeting Kevin Kalinsky MD, Division Director of Breast Medical Oncology from Emory University at the Winship Cancer Institute, Hematology and Medical Oncology, in Atlanta, USA. He told reporter Peter Goodwin more about the details.

An interview with: Wing-Lok Chan MBBS, Clinical Associate Professor, Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China CHICAGO, USA—Patients with advanced cancer had their quality of life preserved and required fewer hospitalizations when they monitored themselves digitally by using the SUPPORT+ mobile phone app prompting better self-management while giving regular access to guidance from a nurse. This was in a randomized controlled study reported to the 2026 Annual Meeting of the American Society of Clinical Oncology by Wing-Lok Chan MBBS, from the Department of Clinical Oncology at the University of Hong Kong, in China. She talked about the findings with Peter Goodwin:

CHICAGO, USA—Patients with unresectable liver cancers who were eligible for treatment with transarterial chemoembolization (TACE), were randomly offered, treatment with the anti-CTL-4 checkpoint inhibitor tremelimumab together with the anti PD-L1 inhibitor durvalumab with or without a third drug: the multiple VEGFR 1, 2 & 3 kinase inhibitor, lenvatinib, in the phase threeEMERALD-3 study. Findings of a significant improvement of progression free survival were reported at the 2026 American Society of Clinical Oncology Annual Meeting by first author Ghassan Abou-Alfa MD PhD from the Gastrointestinal Oncology Service at Memorial Sloan Kettering Cancer Center, in New York and Weill Medical College, Cornell University, New York, NY. After his talk in Chicago Dr. Abou-Alfa gave Peter Goodwin the details:

Patients with RET Fusion Positive Early Stage Non-Small Cell Lung Cancer Benefit from Selpercatinib: LIBRETTO-432 Early Results An interview with: Jonathan W. Goldman MD, Director of Clinical Trials i

Abemaciclib Brings Marked Increase in Progression Free Survival for Patients with Advanced Dedifferentiated Liposarcoma An interview with: Mark A Dickson MD, Medical Oncologist, Associate Attending Ph

Omitting Axillary Lymph Node Dissection: Safe for Patients with Breast Cancer Spread to One or Two Sentinel Lymph Nodes An interview with: Jana de Boniface MD PhD Department of Surgery, Capio St. Göra

Timing of Surgery for Advanced Ovarian Cancer among Neoadjuvant and Adjuvant Chemotherapy Cycles: Early Findings from Randomized CHRONO Trial An interview with: Jean-Marc Classe, MD PhD, Surgeon in Gy

Giredestrant Beats Standard Endocrine Therapies Irrespective of Menopausal Status in Patients with ER+, HER2- Early Breast Cancer An interview with: Peter Schmid MD PhD, Professor of Cancer Medicine;

Immune Checkpoint Inhibitor-Induced Myocarditis within One Month Predicts Lethal “Triple M Overlap Syndrome” An interview with: Hassan Mohammed Abushukair MD, Post-Doctoral Researcher, Oklahoma Univer

Standing ovation at ASCO for RASolute 302 Study

BCMA-directed CAR T-cell Therapy Highly Effective In Patients with High-Risk Smoldering Multiple Myeloma An interview with: Omar Nadeem MD, Medical Oncologist and Clinical Investigator, Dana-Farber Ca

Molecular Glue Brings New Hope for Patients with BRAF or NRAS-Mutant Melanoma or Other RAS/RAF-driven Malignancies An interview with: Ahmad A Tahini MD PhD, Senior Member, Professor, Director, Departm

Wildfires risk more cancer?

AI “Pathomics Platform” Selects Immunotherapy, Predicts Outcome for Patients with Metastatic Non-Small Cell Lung Cancer  An interview with: Rukhmini Bandyopadhyay MD, Postdoctoral Fellow, The Universi

Investigational KRAS(ON) Inhibitor Zoldonrasib Showed Effective and Durable Responses in Patients With Advanced G12D-mutated Lung Cancer An interview with: Jonathan Wesley Riess MD, Professor of Medic

Whole Exome Sequencing of ctDNA Informs Post-Neoadjuvant Therapy Options for Patients with Triple Negative Early Breast Cancer An interview with: Marija Balic MD PhD, Chief of Medical Breast Oncology,

Refractory Ovarian Cancer Yields to Claudin 6 Targeted Antibody Drug Conjugate

oral pre-cancer lesions injected with nivolumab prevented progression with little morbidity

New Generation KRAS G12C Inhibitor Brings Promising Responses Even in Patients with Advanced Lung Cancers Refractory to Previous KRAS-targeted Therapy An interview with Byoung Chul Cho MD PhD, Thoraci