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Tagged: inhibitor

  • Audio Journal of Oncology Volume 16 Number 9
    • in Oncology
    • — 26 Apr, 2008

    Audio Journal of Oncology Volume 16 Number 9

    Scientific Editors: George Canellos (Boston), Pat Price (Manchester), Gianni Bonadonna (Milan), Gordon McVie (Milan)
    Commenting Expert: Emiel Rutgers, Netherlands Cancer Institute, Amsterdam

    Angel Rodriguez
    Angel Rodriguez

    In this edition:

    1. Lapatinib: Targets Breast Cancer Stem Cells?

    Angel Rodriguez, Baylor College, Houston…

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    New Targets Bring Promise For Lung Cancer Therapy
    • in General Medicine
    • — 17 Mar, 2008

    New Targets Bring Promise For Lung Cancer Therapy

    Egbert Smit
    Egbert Smit

    EGBERT SMIT, Free University of Amsterdam
    There are a number of promising new molecular targets for lung cancer chemotherapy which were discussed at the Turin congress by Egbert Smit. He talked with Peter Goodwin about insulin-like
    …
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  • Target Angiogenesis for Lung Cancer With Multiple Tyrosine Kinase Inhibitors
    • in General Medicine
    • — 17 Mar, 2008

    Target Angiogenesis for Lung Cancer With Multiple Tyrosine Kinase Inhibitors

    Silvia Novello
    Silvia Novello

    SILVIA NOVELLO, University of Turin
    Future improvements in drug treatment of lung cancer may be made by inhibiting more than one tyrosine kinase simultaneously. So said Silvia Novello when she presented data on a range of drugs
    …
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    Oral Capecitabine: As Good As Fluorouracil Second Line for Metastatic Colorectal Cancer
    • in Oncology
    • — 15 Feb, 2008

    Oral Capecitabine: As Good As Fluorouracil Second Line for Metastatic Colorectal Cancer

    David Cunningham
    David Cunningham
    REFERENCE: Abstract 3012, ECCO 14, The European Cancer Conference, Barcelona, 23 – 27 September 2007
    DAVID CUNNINGHAM, Royal Marsden Hospital, London
    The oral agent capeticabine is just as effective as fluorouracil for treating patients whose metastatic colorectal cancer
    …
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  • ATAC Trial: Anastrozole Still Superior At Over Eight Years’ Follow Up
    • in Oncology
    • — 15 Dec, 2007

    ATAC Trial: Anastrozole Still Superior At Over Eight Years’ Follow Up

    Jack Cuzick
    Jack Cuzick

    JACK CUZICK, Wolfson Institute of Preventive Medicine, London
    New data from the ATAC trial, which is testing anastrozole and tamoxifen in early breast cancer, have demonstrated the continued superiority of the aromatase inhibitor. Among other things, the data
    …
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    Eptifibatide After PCI: Brief Infusion Is Just As Good
    • in Cardiovascular
    • — 5 Nov, 2007

    Eptifibatide After PCI: Brief Infusion Is Just As Good

    Anthony Fung
    Anthony Fung
    REFERENCE: Late Breaking Clinical Trials Session I, American Heart Association Scientific Sessions, 4-7 November, 2007, Orlando, Florida
    ANTHONY FUNG, University of British Columbia, Vancouver
    Brief courses of antiplatelet therapy with the glycoprotein 2b 3a inhibitor are just as
    …
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  • Bortezomib for Multiple Myeloma Can Cause Reactivation of Viruses
    • in General Medicine
    • — 19 Sep, 2007

    Bortezomib for Multiple Myeloma Can Cause Reactivation of Viruses

    Georg Härter
    Georg Härter

    REFERENCE:47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007
    GEORG HÄRTER, University Hospital, Ulm
    For patients with multiple myeloma being treated with the proteasome inhibitor bortezomib, doctor’s should be wary of viral reactivation – and
    …
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    KRAS Mutation: Powerful Molecular Predictor of Cetuximab Response in Patients With Metastatic Colorectal Cancer
    • in Oncology
    • — 31 Aug, 2007

    KRAS Mutation: Powerful Molecular Predictor of Cetuximab Response in Patients With Metastatic Colorectal Cancer

    Pierre Laurent-Puig
    Pierre Laurent-Puig
    Bill Hait
    Bill Hait

    REFERENCE: ABSTRACT: 5671, American Association for Cancer Research, April 14-18, 2007, Los Angeles
    PIERRE LAURENT-PUIG, Hôpital Européen Georges Pompidou, Paris
    COMMENT: BILL HAIT, Johnson & Johnson, Raritan, NJ

    The presence of the KRAS mutation in tumor
    …
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  • Virus Plus Cytokine Fight Primary and Metastatic Cancer
    • in Oncology
    • — 15 Aug, 2007

    Virus Plus Cytokine Fight Primary and Metastatic Cancer

    Paul Fisher
    Paul Fisher

    REFERENCE: Meet the Professor Session, AACR 2007, Los Angeles
    PAUL FISHER, Columbia University, New York
    Patients with cancer could soon be treated with adenoviruses capable of infecting both primary and distant tumors, and simultaneously releasing cancer-fighting cytokines, according
    …
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    Direct Renin Inhibitor Combined with Angiotensin Receptor Blockade Gives Additional Blood Pressure Lowering
    • in Cardiovascular
    • — 27 Mar, 2007

    Direct Renin Inhibitor Combined with Angiotensin Receptor Blockade Gives Additional Blood Pressure Lowering

    Suzanne Oparil

    SUZANNE OPARIL, University of Alabama, Birmingham

    REFERENCE: Abstract 405-12, American College of Cardiolgy New Orleans
    A combination of two antihypertensive agents has given improved blood pressure control in a study with nearly 2000 patients reported to the ACC meeting in
    …
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  • Integrase Inhibitor Raltegravir Doubles Antiviral Response Rate in Treatment Experienced HIV-Infected Patients Compared to Optimised Background Therapy Alone
    • in Public Health
    • — 6 Mar, 2007

    Integrase Inhibitor Raltegravir Doubles Antiviral Response Rate in Treatment Experienced HIV-Infected Patients Compared to Optimised Background Therapy Alone

    Roy Steigbigel

    John Mellors

    ROY STEIGBIGEL, State University of New York at Stony Brook
    JOHN W. MELLORS, University of Pittsburgh

    REFERENCE: Abstract 105aLB, 105bLB, 14th Conference on Retroviruses and Opportunistic Infections, Los Angeles February 25-28, 2007
    Raltegravir doubled the antiviral response rate and the
    …
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    ASCO Audio Journal of Oncology in Advance – February 1st, 2007 – reporting from American Society of Hematology 48th Annual Meeting, December 9-12, 2006 Orlando
    • in ASCO · Oncology
    • — 3 Feb, 2007

    ASCO Audio Journal of Oncology in Advance – February 1st, 2007 – reporting from American Society of Hematology 48th Annual Meeting, December 9-12, 2006 Orlando

    Francis Giles
    Francis Giles
    Ken Kaushansky
    Ken Kaushansky
    Heather Leitch
    Heather Leitch
    Nancy Berliner
    Nancy Berliner
    Corrado Tarella
    Corrado Tarella
    Vincent Rajkumar
    Vincent Rajkumar
    Robert Kyle
    Robert Kyle

    Aurora Kinase BCR-ABL Inhibitor Beats T315-I Mutation in Patients with Chronic Myeloid Leukemia

    REFERENCE: Abstract: 163
    FRANCIS GILES, M D Anderson Cancer Center, Houston
    COMMENT: KEN

    …
    Read more
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