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Tagged: prostate cancer

  • Which High-Risk Prostate Cancers Need Multimodality Treatment? 0
    • in AJO · Audio · Oncology
    • — 18 Apr, 2017

    Which High-Risk Prostate Cancers Need Multimodality Treatment?

    MILAN, Italy—Patients with node-positive prostate cancer being treated with prostatectomy could derive benefit from early multimodality therapy combining androgen deprivation therapy (ADT) with radiotherapy (RT)—on top of surgery—if they have pathological features indicating high risk, according to findings reported at …

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    Gene Assay Predicts Which Patients Need Radiation After Prostatectomy 0
    • in AJO · Audio · Oncology
    • — 18 Apr, 2017

    Gene Assay Predicts Which Patients Need Radiation After Prostatectomy

    ARTICLE

    MILAN, Italy—Genomic testing combined with clinical assessment could be the best way to identify patients with prostate cancer who can benefit from early radiotherapy after prostatectomy, according to a study in The Lancet Oncology reported at the European Multidisciplinary …

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  • Localized Prostate Cancer—New Study Findings on Active Monitoring versus Early Treatment 0
    • in AJO · Audio
    • — 16 Sep, 2016

    Localized Prostate Cancer—New Study Findings on Active Monitoring versus Early Treatment

    The large randomized Prostate Testing for Cancer and Treatment (ProtecT) study reported in two linked papers in the New England Journal of Medicine—has found that in low and intermediate risk disease radical prostatectomy and radiotherapy did not reduce prostate-specific or …

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    Tumour heterogeneity — clonal evolution of cancer limits effectiveness of targeted systemic therapies 0
    • in Oncology · Video
    • — 26 Mar, 2014

    Tumour heterogeneity — clonal evolution of cancer limits effectiveness of targeted systemic therapies

    SAN FRANCISCO—The ability of cancer cells to evolve clonally into molecularly distinct strands needs to be considered when selecting targeted therapies to treat renal cancer, according to Dr Tom Powles MBBS, MRCP, MD speaking at the ASCO GU Cancers Symposium …

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  • PSA-membrane antibody conjugate shows promise for treating metastatic castration-resistant, taxane-refractory prostate cancer 0
    • in Oncology · Video
    • — 6 Feb, 2014

    PSA-membrane antibody conjugate shows promise for treating metastatic castration-resistant, taxane-refractory prostate cancer

    SAN FRANCISCO—A “guided missile” approach to treating metastatic, castration-resistant, taxane-refractory prostate cancer demonstrated success at the 2014 ASCO Genitourinary Cancers Symposium. Daniel Petrylak MD of Yale University Medical Center in New Haven CT discussed the clinical potential arising from his …

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    Orteronel shows no survival advantage in metastatic castration-resistant prostate cancer: phase III randomized study finds 0
    • in Oncology · Video
    • — 6 Feb, 2014

    Orteronel shows no survival advantage in metastatic castration-resistant prostate cancer: phase III randomized study finds

    SAN FRANCISCO—Orteronel — a non-steroidal selective inhibitor of 17,20-lyase — did not achieve a significant improvement in overall survival in 1099 patients randomised to treatment with this “abiraterone-like” agent in comparison with placebo — though radiographic progression-free survival was improved. …

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