Bilateral Mastectomy and Salpingo-Oophorectomy Significantly Extend Survival In BRCA-mutation Carriers Who Already Have Breast Cancer
The important question of whether to recommend risk-reducing surgery to patients who are carriers of pathogenic mutations in either BRCA1 or BRCA2 genes (or both), and have already developed breast cancer, has been investigated in a study from Italy reported at the 2025 San Antonio Breast Cancer Symposium.
Researcher Matteo Lambertini MD PhD, from the University of Genoa, Assistant Professor and Consultant in Medical Oncology at the San Martino IST Hospital in Genoa, Italy, gave the details to Audio Journal of Oncology correspondent Peter Goodwin.
SABCS ABSTRACT TITLE:
“Association between risk-reducing surgeries and survival in young BRCA carriers with breast cancer: results from an international cohort study”
